Rediscover Comfort and Vitality
Advanced non-surgical treatments to relieve vaginal dryness, discomfort, urinary issues, and other menopausal symptoms with natural, long-lasting results.
Our Estrogen Replacement Treatment
The Re3 Advanced Pellet Delivery System
Pellecome Estrogen Pellet Therapy
Pellecome’s bioidentical hormone replacement therapy (BHRT) uses subcutaneous estrogen pellets to relieve the physical and metabolic symptoms associated with menopause. As estrogen levels decline, many women experience hot flashes, night sweats, vaginal dryness, thinning skin, urinary symptoms, and even bone loss. Pellecome pellets offer a sustained, physician-guided delivery of estrogen to restore hormonal balance and improve quality of life.
Key benefits of Pellecome Estrogen Pellet Therapy include:
This hormone therapy is individualized based on your lab results, medical history, and symptoms, and is typically administered every 3–6 months. Our physicians monitor your response closely to ensure optimal safety and effectiveness.

Comprehensive Menopausal Wellness
At Pacific Clinic, we understand that post-menopausal symptoms can affect multiple aspects of your life. Our physicians take a holistic approach to your treatment, which may include:
This comprehensive approach ensures that we address the full spectrum of your post-menopausal concerns for the best possible quality of life.
The Treatment Process
Frequently Asked Questions
Patient comfort is our priority. We use topical or local anesthetic and offer Nitronox (medical nitrous oxide) to ensure a comfortable experience. Most patients report minimal discomfort—typically just a mild pressure sensation during the procedure.
Many women notice initial improvements in vaginal comfort and lubrication within days of treatment. However, the full benefits develop over several weeks. For the O-shot patients, experience continued improvement for up to 3 months after the procedure. Results typically last 1-2 years. The benefits of the Pellecome Estrogen Pellet therapy last 3-6 months requiring regular follow up and treatment adjustments. For MonaLisa Touch, some patients experience continued improvement for up to 3-4 months after the procedure. Results typically last 1-2 years, though this varies based on individual factors.
MonaLisa Touch®
- MonaLisa Touch® is widely viewed as a dependable option for post-menopausal women looking for relief from dryness, irritation, or discomfort. The gentle CO₂ laser works directly on the vaginal tissues, encouraging natural renewal without introducing hormones—making it appealing for women who can’t use or prefer to avoid hormone therapy. Most patients find the treatment quick, comfortable, and easy to fit into their routine. A consultation will help confirm that it’s a good match for your specific needs and goals.
O-Shot
- Yes, the O-Shot is particularly well-suited for post-menopausal women because it uses your body’s own natural growth factors rather than hormones. This makes it an excellent option for women who cannot or prefer not to use hormone-based treatments.
Pellecome Estrogen Pellet Therapy
- Pellecome pellet therapy is a safe, evidence-based solution for estrogen replacement. The bioidentical pellets are precisely dosed and inserted subcutaneously for gradual, sustained hormone delivery. This method avoids the hormone fluctuations and compliance issues associated with daily pills or creams.
- Most women experience improvements within the first few weeks, with optimal results developing over the first 1–2 months. Treatment typically lasts 3–6 months before another pellet is needed. Your physician will monitor hormone levels over time and make dosage adjustments as needed to maintain balance and effectiveness.
Yes, the O-Shot works well both as a standalone treatment and in combination with Pellecome Estrogen pellets for post-menopausal symptoms. Some women choose to combine it with low-dose topical estrogen or other treatments for comprehensive symptom management.
Yes — you can receive MonaLisa Touch® even if you’re currently using hormone replacement therapy (HRT).
Many patients combine the two because they work in different ways. HRT supports hormone levels throughout the body, while MonaLisa Touch® focuses specifically on the vaginal tissues by encouraging collagen renewal, boosting elasticity, and helping restore natural moisture.
If HRT has helped but you’re still dealing with symptoms such as dryness, discomfort during intimacy, or urinary changes, MonaLisa Touch® can offer added relief. It’s also a helpful choice for women who prefer to keep hormone doses lower or who don’t tolerate increases well.
Be sure to let your provider know you’re on HRT so they can design a treatment plan that fits your needs.
MonaLisa Touch®
- Noticeable results occur after only 1 session but to be fully effective a series of 3 sessions are necessary. Some patients may require 4-5 treatments depending on the severity of their condition. Each treatment session is 30 minutes and scheduled 6 weeks apart.
- Maintenance includes an annual MonaLisa Touch® up. As the aging process continues symptoms will gradually return. An annual touch up will protect your initial investment by avoiding repeating all 3 treatments. Individual results may vary.
O-Shot
- Many women achieve significant symptom relief with just one O-Shot treatment. However, depending on the severity of your symptoms and your response to the initial procedure, our physicians may recommend a second treatment after 8-12 weeks for optimal results. Annual maintenance treatments can help preserve the benefits long-term.
Pellecome Estrogen Pellet Therapy
- Depending on the severity of your symptoms and your response to the initial procedure, our physicians may recommend follow up treatments every 3-6 months for optimal & long-lasting results.
Reclaim Your Comfort
Post-menopausal symptoms don’t have to diminish your quality of life or intimate relationships. At Pacific Clinic in Bellevue, our physician-led, non-surgical approach offers a path to renewed comfort and con
